The transatlantic broadcast from Wembley Stadium suffered technical problems and failed during The Who's performance of their song "My Generation", immediately after Roger Daltrey sang "Why don't you all fade..." (the last word was cut off when a blown fuse caused the Wembley stage TV feed to temporarily fail). The Who were playing with Kenney Jones on drums, who was still an official member of The Who at this time, although this was their first performance since they'd officially disbanded after their 1982 'farewell' tour. The Who's performance included an at times shambolic, but still blistering version of "Won't Get Fooled Again", which was extremely popular with the audience in Wembley Stadium. The band's performance was described as "rough but right" by Rolling Stone magazine, but they would not perform together again until the 1988 BPI Awards.

At the conclusion of the Wembley performances, Bob Geldof was raised heroically onto the shoulders of The Who's guitarist Pete Townshend and McCartney – symbolising his great achievement in unifying the world for one day, in the spirit of music and charity.

At the very beginning of the televised portion of the Philadelphia concert, Joan Baez announced to the assembled crowd (and the viewing audience) that "this is your Woodstock, and it's long overdue", before leading the crowd in "Amazing Grace" (paired with a couple of verses of "We Are the World").

When Madonna got on stage, despite the 95°F ambient temperature, she proclaimed "I'm not taking shit off today!" referring to the recent release of early nude photos of her in Playboy and Penthouse magazines.

During his opening number, American Girl, Tom Petty flipped the middle finger to somebody off stage about one minute into song. Petty stated the song was a last minute addition when the band realised that they would be the first act to play the American side of the concert after the London finale and "since this is, after all, JFK Stadium".

When Bob Dylan broke a guitar string, Ronnie Wood took off his own guitar and gave it to Dylan. Wood was left standing on stage guitarless. After shrugging to the audience, he played air guitar, even mimicking The Who's Pete Townshend by swinging his arm in wide circles, until a stagehand brought him a replacement. Although this moment was left off the DVD, the performance itself was included, featuring footage focusing solely on Keith Richards.

During their duet on "It's Only Rock 'n' Roll", Mick Jagger ripped away part of Tina Turner's dress, leaving her to finish the song in what was, effectively, a leotard.

The JFK portion included reunions of Crosby, Stills, Nash & Young, the original Black Sabbath with Ozzy Osbourne, and former members of Led Zeppelin, with Phil Collins and Chic member Tony Thompson sharing duties on drums (although they were not officially announced by their group name from the stage, but were announced as Led Zeppelin on the VH1 10th Anniversary re-broadcast in 1995).

Teddy Pendergrass made his first public appearance since his near-fatal car accident in 1982 which paralysed him. Pendergrass, along with Ashford & Simpson, performed "Reach Out and Touch".